ea0041oc4.3 | Thyroid - Clinical | ECE2016
Molnar Ildiko
, Szentmiklosi Jozsef A
, Somogyine-Vari Eva
Type 2 5-deiodinase (DIO2) is a common enzyme between thyroid and eye muscle tissues involving in T4 conversion to T3. The role of DIO2 has been demonstrated in the development of skeletal muscle. Increased DIO2 activities was connected to eye muscle enlargements in hyperthyroid Graves ophthalmopathy. In this study, the presence of antibodies against human eye muscle tissue fractions with the binding to DIO2 peptide was investigated and measur...